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🩸 Blood Work

What do LH and FSH numbers mean on a pre-TRT lab report?

Asked in r/trt · Answered by the HeydayMD team ·

I just got my baseline hormone panel back and saw numbers for luteinizing hormone and follicle-stimulating hormone. How do these pituitary markers factor into diagnosing hypogonadism?

The short answer

Luteinizing hormone (LH) and follicle-stimulating hormone (FSH) are pituitary hormones that signal the testes to produce testosterone and support reproductive function. When evaluating low testosterone, checking these gonadotropins helps clinicians distinguish between primary hypogonadism originating in the testes and secondary hypogonadism linked to pituitary signaling. Elevated LH and FSH with low testosterone point toward testicular issues, while low or normal levels often suggest a central signaling problem. Discussing these specific patterns with your licensed MD, NP, or PA is essential for an accurate diagnosis and appropriate care plan.

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The information on this page is for educational purposes only and is not medical advice. Questions are paraphrased from public Reddit discussions, which are linked for reference — HeydayMD is not affiliated with Reddit. Answers are general education written by the HeydayMD team, not individual guidance. Always talk to a licensed healthcare provider before making treatment decisions.