Has anyone noticed getting sick more or less often since starting TRT?

Testosterone interacts with the immune system in complex ways, as androgen receptors are present on various immune cells, meaning optimized levels generally support a balanced immune response rather than suppressing it. While some men report feeling more resilient to seasonal bugs once their hormone levels are dialed in, a sudden increase in the frequency of illness is usually tied to external factors like stress, sleep disruption, or underlying nutritional deficiencies rather than TRT itself. At HeydayMD, our clinical team takes a holistic look at your overall health markers and lifestyle factors to ensure your testosterone replacement protocol supports your long-term immune resilience and vitality.