Treatments
All Treatments Online TRT GLP-1 Weight Loss Sleep Apnea Lab Kit
Learn
Education Center All Articles TRT Pulse ⚡ Community Q&A 💬 FAQ
Company
Providers Reviews Take The Quiz →
🩸 Blood Work

Worried about my lipid panel after 6 months on TRT - HDL dropping?

Asked in r/trt · Answered by the HeydayMD team ·

I've been on 150mg/week for about half a year now and feeling great, but my recent blood work shows my HDL has tanked while my LDL ticked up slightly. My doctor is concerned about heart health, but I don't want to stop treatment. Has anyone else dealt with this or found a way to manage it?

The short answer

It is common to see a decrease in HDL (good cholesterol) and a slight increase in LDL when starting testosterone replacement therapy, as androgens can influence lipid metabolism. While these changes are often mild, it is important to monitor your cardiovascular markers and maintain a heart-healthy lifestyle through diet and exercise. In some cases, adjusting your dosage or frequency can help stabilize these numbers without sacrificing the benefits of your treatment. At HeydayMD, our clinical team specializes in interpreting these specific markers to ensure your hormone optimization remains safe and effective for your long-term heart health.

Every body is different. A licensed provider can look at your own labs and symptoms.

Take The Quiz →

The information on this page is for educational purposes only and is not medical advice. Questions are paraphrased from public Reddit discussions, which are linked for reference — HeydayMD is not affiliated with Reddit. Answers are general education written by the HeydayMD team, not individual guidance. Always talk to a licensed healthcare provider before making treatment decisions.