Treatments
All Treatments Online TRT GLP-1 Weight Loss Sleep Apnea Lab Kit
Learn
Education Center All Articles TRT Pulse ⚡ Community Q&A 💬 FAQ
Company
Providers Reviews Take The Quiz →
🧠 Mental Health

Dealing with mood swings, anxiety, and depression on TRT?

Asked in r/Testosterone · Answered by the HeydayMD team ·

The poster is experiencing emotional instability, including anxiety and depression, while on testosterone replacement therapy and is considering checking DHEA and Pregnenolone levels.

The short answer

Mood swings, anxiety, and depression on TRT are often linked to hormonal imbalances, particularly fluctuations in estradiol or deficiencies in neurosteroids like DHEA and Pregnenolone. While checking these levels is a great step, it's also crucial to evaluate your injection frequency to ensure stable blood serum levels. At HeydayMD, we specialize in comprehensive hormone optimization that looks beyond just testosterone to address these mental health symptoms. Our clinical team can help you fine-tune your protocol to eliminate these 'rollercoaster' effects and restore emotional stability.

Read our full guide →

Every body is different. A licensed provider can look at your own labs and symptoms.

Take The Quiz →

The information on this page is for educational purposes only and is not medical advice. Questions are paraphrased from public Reddit discussions, which are linked for reference — HeydayMD is not affiliated with Reddit. Answers are general education written by the HeydayMD team, not individual guidance. Always talk to a licensed healthcare provider before making treatment decisions.