Sex drive tanked after adding semaglutide to my TRT—GLP-1 or weight loss?
I've been on a stable TRT dose for over a year with great drive, but ever since adding a GLP-1 for cutting, my libido has completely flatlined.
Combining a GLP-1 like semaglutide with TRT can sometimes cause temporary dips in libido, often driven by sharp caloric restriction, rapid metabolic shifts, or the peptide's direct effects on dopamine pathways. While your testosterone protocol keeps baseline hormone levels supported, aggressive weight loss can temporarily impact free hormone availability and overall energy reserves. At HeydayMD, our clinical team monitors your comprehensive metabolic and hormonal panels to help you fine-tune your stack, ensuring your weight-loss goals don't come at the expense of your vitality.
Every body is different. A licensed provider can look at your own labs and symptoms.
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